醫學系黃雅君

2014 APCN Tokyo poster presentation心得      

          還記得這一切的開始只是深夜的一則line訊息。
          “今年的APCN在東京舉辦，再過兩個禮拜要截止收abstract, 你有興趣寫abstract去投稿嗎?” 腎內的林祐賢醫師突然傳了line給我。但真正吸引我的是後面那句話。”如果被accept的話學校會補助機票，科內也會補助住宿，到時候就可以去東京玩喔!!”
         於是我毫不猶豫地回傳(無視截止期限的急迫)”好啊~那再跟老師約時間討論”
         至於為什麼林醫師會連絡我，是因為我參加了腎臟內科的研究計畫，由洪啟智老師指導生物統計技巧、分配topic、並指導寫論文，而負責聯絡跟監督的就是林醫師。
        在跟林醫師敲定好約在大同醫院的討論時間後，我便開始著手研究被分配到的topic. 雖說一個完整的data base, table 1-4都在眼前，但是對一個研究領域的新手而言，要無中生有，憑空在短時間內寫出一篇abstract，難度猶如越級打怪般高……即使老師貼心的準備了範本，寫起來依然覺得如墜五里霧中。
        幸好在老師的專業指導、不耐其煩的指正以及互相討論之下，abstract還是如期生出! (和另一位第一作者兼好友，花了許多時間研究大會的英文網站，並成功投稿abstract則又是另一個故事了XD) 今年二月，終於收到令人興奮的消息: 我們的論文摘要已經被接受! 之後又寄信給我們確認發表日期及細節，收到信的時候有種美夢成真的感覺，好像人已經身在東京了XD 而腎臟科主任陳鴻鈞也很大力幫忙，除了表示贊助住宿品川王子飯店之外(因為這次APCN的地點就在品川王子的宴會廳)，也十分關心我們的安全(最後被accept的三個人都是女生)，並說我們還是以安排旅遊為主，不必被會期綁住 (太感動了QQ)
        在此附上APCN這次簡介及詳細行程，讓大家更能了解我們參加會議的形式:
1. Congress overview

Title:	The 14th Asian Pacific Congress of Nephrology
Date:	May 14 (Wed) - 17 (Sat), 2014
Venue:	Shinagawa Prince Hotel, Annex Tower 5F "Prince Hall"
Congress President:	Yasuhiko Tomino
Secretary General:	Yusuke Suzuki
Treasurer:	Hitoshi Suzuki
Website:	http://www.mtoyou.jp/apcn2014/
Congress Secretariat:	Division of Nephrology, Department of Internal Medicine, Juntendo University Faculty of Medicine 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421 JAPAN E-mail: apcn2014org@mtoyou.jp
General Inquiry:	c/o Medical TOYOU Co. Ltd. 3-5 Izumi-cho, Atsugi-shi, Kanagawa 243-0013 JAPAN E-mail: apcn2014@mtoyou.jp

2.會期間詳細的symposium跟project
May 14 (Wed), 2014

JSN 2013 and APCN 2014 Cooperative Project      13:00-16:50, Room 1

Young Investigators Award for Asian Nephrologists (YIAAN) Session

Chairs: Seiichi Matsuo (Japan), David Harris (Australia)

YS-01	Uric acid-induced NLRP3 inflammasome contribute to diabetic kidney injury Ju-Young Moon (Korea)
YS-02	Proximal renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes by retaining NMN. Kazuhiro Hasegawa (Japan)
YS-03	Glyoxalase-1 inhibition leads to podocyte insulin resistance and features resembling diabetic kidney disease Linda Gallo (Australia)
YS-04	Potential role of MRP8 in glomerular injury through intraglomerular crosstalk affecting macrophage characterization Takashige Kuwabara (Japan)
YS-05	A predictive model for 3-month mortality risk among chronic kidney disease patients initiating hemodialysis Vidhia Umami (Indonesia)
YS-06	Oligonephronia and focal segmental glomerulosclerosis development in KIF26A deficient mice Chiwei Lee (Japan)
YS-07	Single versus Double Antibiotics for Bacterial Peritonitis in Continuous Ambulatory Peritoneal Dialysis Patients: A Multicenter, Randomized Controlled Trial Nalinee Saiprasertkit (Thailand)
YS-08	Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice Eisei Sohara (Japan)
YS-09	The effect of dialysis modality switch on residual renal function in patient with stage 5 chronic kidney disease. A post hoc analysis from the IDEAL trial Mugeot Wong (Australia)
YS-10	Clinical usefulness of CKD classification combined albumimnuria with estimated glomerular filtration rate in a HIV population: A multicenter study in Japan Naoki Yanagisawa (Japan)

Sponsored Lecture      17:00-18:30, Room 1

Present and Future Mission in Asian Pacific Nephrology - Perspective and Challenge -

Chair: Yasuhiko Tomino (Japan)

Situation of Nephrology in Asia -2014
    Speaker: Kriang Tungsanga (Thailand)

Uncertain Times: Our common agenda
    Speaker: Kiyoshi Kurokawa (Japan)

Co-sponsored by Daiichi Sankyo Co., Ltd.

May 15 (Thu)

Symposium 1      8:45-11:45, Room 1

Diabetic kidney disease

Chairs: Takashi Wada (Japan), Daniel Tak Mao Chan (Hong Kong)

Short overview: Masakazu Haneda (Japan)

SY1-1	Clinical significance of urinary liver type fatty acid binding protein (L-FABP) in diabetic nephropathy Atsuko Ikemori (Japan)
SY1-2	Clinico-pathological factors associated with outcomes in diabetic kidney disease Kengo Furuichi (Japan)
SY1-3	The Role of Metallothionein in Diabetic Nephropathy Daisuke Ogawa (Japan)
SY1-4	Pathogenesis and treatment of diabetic nephropathy, what we have learned from proteomics and miRNA Qiuling Fan (China)
SY1-5	Overview of diabetes and its complication (in asia) Agung Pranoto (Indonesia)
SY1-6	Role for uric acid, as a metabolite of fructose, in diabetic tubular injury Takahiko Nakagawa (Japan)

Symposium 2      8:45-11:15, Room 3

Acute Kidney Injury

Chairs: Hirokazu Okada (Japan), Robert J. Walker (New Zealand)

Introduction: Yoshihide Fujigaki (Japan)

SY2-1	An overview for topics of acute kidney injury Hideo Yasuda (Japan)
SY2-2	Pathogenesis of acute kidney injury Sang-Kyung Jo (Korea)
SY2-3	Urinary biomarker for acute kidney injury (AKI) Yukio Yuzawa (Japan)
SY2-4	Acute blood purification for AKI Kent Doi (Japan)
SY2-5	Drug therapy for acute renal injury: we need better therapy from bench to bedside Yoshio Terada (Japan)

Symposium 3      13:30-16:00, Room 1

IgA nephropathy (Basic)

Chairs: Ichiei Narita (Japan), Jan Novak (US)

SY3-1	Variants in genes encoding complement regulatory proteins affect IgA initiated complement activation in IgA nephropathy Hong Zhang (China)
SY3-2	Whole exome sequencing analysis in Japanese familial IgA nephropathy Shin Goto (Japan)
SY3-3	New Insights into the Pathogenesis of IgA nephropathy Jonathan Barratt (UK)
SY3-4	IgA Nephropathy: Pathogenetic Pathways and Implications for Disease-Specific Treatment and Biomarkers Jan Novak (US)
SY3-5	Pathological role of palatine tonsil in IgA nephropathy Yusuke Suzuki (Japan)

Symposium 4      13:30-16:00, Room 2

Hypertension

Chairs: Atsuhiro Ichihara (Japan), Gavin J. Becker (Australia)

Keynote lecture: Akira Nishiyama (Japan)

SY4-1	Salt-sensitive hypertension Ji-Guang Wang (China)
SY4-2	Hypertension and target organ damages with metabolic risk factors Chang-Gyu Park (Korea)
SY4-3	Renal sympathetic nervous system and hypertension Satoshi Morimoto (Japan)
SY4-4	Chronic kidney disease and cardiovascular risk Satoko Nakamura (Japan)
SY4-5	CKD and blood pressure, Japanese epidemiological evidence Tae Yamamoto (Japan)

Symposium 5      13:30-16:00, Room 3

IgG4-related kidney disease

Chairs: Hitoshi Sugiyama (Japan), Craig L Nelson (New Zealand)

SY5-1	Overview: IgG4-related disease and IgG4-related kidney disease Mitsuhiro Kawano (Japan)
SY5-2	Characteristic Pathology of IgG4-Related Kidney Disease Michio Nagata (Japan)
SY5-3	Clinical aspects of IgG4-related kidney disease Takako Saeki (Japan)
SY5-4	Alternative Th2 response in IgG4-related kidney disease Hitoshi Nakashima (Japan)
SY5-5	Pathogenesis and multiple organ involvements in IgG4-related disease Yoh Zen (UK)

May 16 (Fri)

Asian Forum of CKD Initiative (AFCKDI)      9:00-16:55, Room 1

Symposium 6      9:00-11:30, Room 3

Nephrotic Syndrome and Podocyte Biology

Chairs: Shoichi Maruyama (Japan), Tobias B. Huber (Germany)

Short overview: Katsuhiko Asanuma (Japan)

SY6-1	The Urinary Podocyte and Its Clinical Significance Masanori Hara (Japan)
SY6-2	Unravelling the slit diaphragm protein complex Tobias B. Huber (Germany)
SY6-3	Japan Nephrotic Syndrome Cohort Study (JNSCS): A nationwide prospective cohort study of primary nephrotic syndrome in Japan Ryohei Yamamoto (Japan)
SY6-4	Clinical features, Pathological findings and Prognosis of the Patients with Nephrotic Syndrome in Korea Dong-Wan Chae (Korea)
SY6-5	Podocyte Injury Enhances Filtration of Liver-derived Angiotensinogen And Renal Angiotensin II Generation Taiji Matsusaka (Japan)

Symposium 7      14:15-16:30, Room 3

Renal regeneration

Chairs: Motoko Yanagita (Japan), Sydney C. W. Tang (Hong Kong)

Short overview: Takashi Yokoo (Japan)

SY7-1	Renal regeneration in Zebrafish Alan Davidson (New Zealand)
SY7-2	Renal Regeneration in Proteinuric CKD Sydney C. W. Tang (Hong Kong)
SY7-3	Directed differentiation of kidney lineage cells from human iPSCs/ESCs Kenji Osafume (Japan)
SY7-4	Redefining the in vivo origin of nephron progenitors enables generation of three-dimensional glomeruli and renal tubules from pluripotent stem cells in vitro Ryuichi Nishinakamura (Japan)
SY7-5	Directed differentiation of pluripotent stem cells to form a self-organising kidney Melissa Little (Australia)

May 17 (Sat)

Symposium 8      9:00-11:30, Room 1

IgA nephropathy (Clinical/KDIGO)

Chairs: Tetsuya Kawamura (Japan), Jonathan Barratt (UK)

SY8-1	KDIGO Clinical Practice guideline on the treatment of IgA nephropathy Philip Li (Hong Kong)
SY8-2	The first comprehensive evidence-based clinical guideline for IgA nephropathy in Japan Yukio Yuzawa (Japan)
SY8-3	Clinical Practice for IgA Nephropathy in China Zhi-Hong Liu (China)
SY8-4	The predictive value of the Oxford classification of IgA nephropathy in cohorts with different presentations and receiving different treatments: the VALIGA study Rosanna Coppo (Italy)
SY8-5	A multicenter randomized controlled trial of tonsillectomy combined with steroid pulse therapy in patients with IgA nephropathy Tetsuya Kawamura (Japan)
SY8-6	Interim analysis of the nationwide retrospective cohort study in IgA nephropathy in Japan Takashi Yasuda (Japan)
Additional remarks: Ritsuko Katafuchi (Japan), Hitoshi Suzuki (Japan)

Panel Discussion  13:30-15:00, Room 1

IgA nephropathy (Clinical/KDIGO)

Chairs: Yasuhiko Tomino (Japan), Rosanna Coppo (Italy)

Panelists: Dong-Wan Chae (Korea), Jonathan Barratt (UK),
                Jukka Mustonen (Finland), Yoshinari Yasuda (Japan),
                Ryohei Yamamoto (Japan), Keita Hirano (Japan)

Sponsored Seminar  15:00-16:00, Room 1

IgA nephropathy closing remark

Chair: Yasuhiko Tomino (Japan)

Concluding Remarks and Perspectives on IgA Nephropathy-2014
    Speaker: Richard Glassock (US)

Co-sponsored by Kyowa Hakko Kirin Co., Ltd.

Symposium 9      9:00-11:30, Room 3

Renal replacement therapy

Chairs: Kosaku Nitta (Japan), Christian Combe (France)

Short overview: Kunihiro Yamagata (Japan)

SY9-1	Advanced CKD in Europe and France: Treatment strategies and their initiation Christian Combe (France)
SY9-2	TBC Bruce Cooper (Australia)
SY9-3	Dialysis initiation in Taiwan Shang-Jyh Hwang (Taiwan)
SY9-4	Preemptive Renal Transplantation Adrian Liew (Singapore)
SY9-5	Pediatric end stage kidney disease (ESKD) patients in Japan Motoshi Hattori (Japan)
SY9-6	Dialysis Initiation in Japan Kunihiro Yamagata (Japan)

Symposium 10      14:00-16:00, Room 3

Renal replacement therapy·KDIGO·Anemia

Chairs: Kazuhiko Tsuruya (Japan), Peter G. Kerr (Australia)

SY10-1	Optimizing management strategies and individualizing treatment approaches for anemia and CKD: A KDIGO perspective Lawrence P. McMahon (Australia)
SY10-2	Erythropoiesis-Stimulating Agents in Renal Anemia: What we learned in Taiwan Der-Cherng Tarng (Taiwan)
SY10-3	Anemia management and outcomes in patients with chronic kidney disease: From a clinical research center for end-stage renal disease in Korea Sun-Hee Park (Korea)
SY10-4	Anemia management in Japan: comparison of guidelines Masaomi Nangaku (Japan)

  不得不說這次真的是個難得的經驗，雖然有許多symposium沒有機會參加到，但是這是第一次參加國際學術會議，並發表成果。讓我覺得自己好像又拓展了一點視野，往舒適圈外又踏了一步。
  而在發表的過程中，由於選的是poster presentation, 形式就是把海報貼到指定的看板上，在大會指定的時間乖乖站在自己的海報前讓過往各國學者教授詢問。當然也可以去看看其他人的發表成果。如果說過程有什麼挫折的話，大概就是語言的隔閡了! 許多意思無法用英文完整流利的表達出來，心有餘而力不足…….另外一方便，日本教授們的口音有時也比較難以理解，一來一往之間，往往花最多時間是在確認理解彼此的意思，無法能有更深刻、無barrier的交談，真的很可惜。
  而在東京待了一個禮拜，除了準備發表之外，當然就是和好朋友自助走透透的過程最令人難忘了!除了豐富的文化體驗之外，還有不可或缺的逛街行程，這是我第一次規畫自助旅遊，途中帶來的衝擊及省思令人激盪。在此介紹我旅途中最喜歡的三鷹(宮崎駿博物館)跟吉祥寺:
  交通:

(1)   山手線到神田，轉中央線(過17站)到三鴈 or 新宿站乘JR中央線約20分鐘抵達三鷹站。從三鷹站南口搭乘開往吉卜力美術館之連絡巴士 單程票200日圓/ 來回票300日圓(當場購票)

(2)   三鷹車站→美術館: 坐到三鷹,然後走路到宮崎駿博物館(10am-6pm開館，走路15分鐘)或坐龍貓巴士十分鐘一班, 從三鷹到吉卜力美術館的路程，強烈建議用走的！從三鷹車站南口出來，在三鷹之森美術館的公車站旁，有「風之散步道」的指標，標示是1500公尺。就是出車站後向左走到底，下天橋（因為一出車站你就在天橋上啦），一直走沿著「玉川上水」，很美！一路上都有指標，大約走10~15分鐘就到美術館了，搭公車則頗擠!

(3)   吉卜力→吉祥寺：從美術館出來，穿過井之頭恩賜公園就會到吉祥寺，雖然公園真的很漂亮，但是到車站的距離至少有兩公里以上，邊走邊上廁所要30分鐘左右。如果比較累了建議用坐車的,一出公園在走到吉祥寺, 前有一家燒烤店，超讚!便宜又好吃!

  吉祥寺---藥妝、古著(多且比下北澤便宜)、伴手禮(多而便宜)

1.      穿過吉祥寺車站，出車站「中央口」(北口)，一直延伸出去到五日市街道的的商店街叫做「太陽道商店街」SUN ROAD，是台灣人最愛的藥妝採購一級戰區，也是服飾店與餐廳等小店聚集地，也可通往東急、PARCA或伊勢丹百貨公司，太陽道(Sun Road)商店街除了藥妝以外，也有多間鞋店、服飾店，或是咖啡廳等小餐館。要補DHC貨品，或是喜歡一蘭拉麵的，這邊也找得到。

2.      藥妝店：比東京的便宜(周五六日還會有拍賣會更便宜) 每間最低價都不同 自己選~但都最便宜!

這次的旅程收穫良多，不但代表高醫參加國際學術會議，見識這樣的場面及氣度，也滿足了旅遊的癮。希望能夠在研究領域上再接再厲，下次還能有機會代表母校出去爭光。