醫技碩二江亭蕙出國研習心得
研習時間:1000816~1000820
研習地點:斯洛伐克 Slovakia
研習名稱:2011年亞太質譜年會
研習類別:國際會議(發表論文-Poster)
1、 參加會議經過
因為這次的機會所以有機會第一次到韓國，所以就安排了幾天先到韓國首都首爾市觀光，記憶中張貼海報時間是8月17日早上9點前，所以8/17日當天清晨4.5點起床從首爾車站搭乘6點第一班快速鐵路到達釜山市，約9點半左右到達會場BEXCO釜山展覽中心，報到櫃台竟然空無一人，四處找尋終於找到穿著制服的工作人員，原來是我們搞錯開幕時間了。等到了下午終於開始報到了，緊湊的會議也開始進行，8/18日晚上主辦單位還熱情的準備了晚宴讓與會的會員可以相互認識聯絡感情，8/19日抱著興奮的心情就去會場完成了我的海報張貼。以下就是這次緊湊的會議議程時間表：
August 18, 2011
Session 1 - Mass Spectrometry Driven Proteomics,8:50 - 11:40 AM
Room: Convention Hall 2F (203+204)
Chairs: Dr. Yuju Chen (Academia Sinica) & Dr. Yoshinao Wada (Japan representative)
Mass spectrometry revolutionizes biological sciences. Especially, mass spectrometry plays integral roles in researches of proteomics, where whole proteomes of biological systems are analyzed in the context of their responses either to internal changes or external stimuli, the global networks of molecular interactions, and the accurate identification of complex responses to disease states. In this session, current issues and recent developments of mass spectrometry driven proteomics will be discussed.
8:50 - 9:10 AM
Prof. Yasushi Ishihama (Kyoto University, Japan)
One-Shot Phosphoproteome Analysis by UnidimensionalNanoLC-MS/MS with Highly Efficient Phosphopeptide Enrichment
9:10 - 9:30 AM
Prof. KwangPyo Kim (KonKuk University, Korea)
Systematic Discovery of Nitrated Tyrosine motifs in Nitroproteomics using Affinity Enrichment and LC/MS/MS
9:30 - 9:50 AM
Dr. Pengyuan Yang (Fudan University, China)
Mass Spectrometry Profiling of N-glycopeptides from Serum
9:50 - 10:10 AM
Prof. Hyun JooAhn (Chung Nam National University, Korea)
Human Cell Membrane Glycan Mapping using Mass Spectrometry
Coffee Break (10:10 - 10: 20 AM)
10:20 - 10:40 AM
Prof. Daehee Hwang (Pohang University of Science and Technology, Korea)
Decoding Proteomic Signature Predictive of Chemoresistance in Breast Cancers
10:40 - 11:00 AM
Prof. Siu Kwan Sze (Nanyang Technological University, Singapore)
Roles of Mitochondrial Protein Kinases in Targeted Cancer Therapy
11:00 - 11:20 AM
Prof. Shu-Hui Chen (National Cheng Kung University, Taiwan)
Quantitative Proteomics and Affinity Purifications for Estrogen-Triggered Signal Transduction
11:20 - 11:40 AM
Prof. Manfred Raida (A*STAR, Singapore)
Targeted Mass Spectrometry for Biomarker Detection, Pitfalls and Solutions
Session 2 - Recent Advances in Metabolomics,2:00 - 4:00 PM
Chairs: Dr. Bong Chul Chung (Korea Institute of Science and Technology)&Dr. Mustafa Ali Mohd (Malaysia Representative)
In contrast to classical bio-analyses that mainly focus on single metabolites and/or defined sets of linked reactions and cycles, metabolomics involves the collection of quantitative signatures on a broad series of metabolites to understand metabolic dynamics associated with biological conditions of interest. In this session, recent advances in both method development and biomedical applications for mass spectrometry based metabolomics will be discussed.
2:00 - 2:20 PM
Prof. Zhou Lei (National University of Singapore, Singapore)
Human Tear Proteomics, Metabolomics and Biomarker Discovery in Eye Diseases
2:20 - 2:40 PM
Dr. ZongweiCai (Hong Kong Baptist University, Hong Kong SAR, China)
Mass spectrometry-based metabolomics investigation of aristolochic acids associated with kidney disease
2:40 - 3:00 PM
Prof. GuowangXu (Dalian Institute of Chemical Physics, The Chinese Academy of Science, China)
A functional metabolomics platform based on non-target and target chromatography-mass spectrometry
3:00 - 3:20 PM
Dr. Man-Ho Choi (Korea Institute of Science and Technology, Korea)
Hair Metabolomics in clinical applications of the skin-appendage diseases
3:20 - 3:40 PM
Dr. Anne Bendt (National Unversity of Singapore, Singapore)
Lipidomics: New tools and applications
3:40 - 4:00 PM
Dr. Young-Ran Yoon (KyungpookNational University, Korea)
Metabolomics for Pharmacokinetics, Drug Efficacy, and Drug Toxicity
Session 3 - Fundamentals of Mass Spectrometry I,4:10 - 5:50 PM
Chairs: Dr. Hyun Sik Kim (Korea Basic Science Institute)&Dr. Ryuichi Arakawa (President of MSSJ, Japan representative)
As mass spectrometry is used in biotechnology and nanotechnology more frequently than ever, soft ionization and tandem mass spectrometry are blooming as main players in the field of mass spectrometry. Fragmentation of molecular ions is an essential process of structural elucidation of unknown compound. However, it reduces sensitivity to detect the limited amount of molecular ions generated by ionization techniques. Thereby, better understanding of the fundamental parameters to control the fragmentation process is important. Recent progress of basic understanding in ionization, fragmentation and gas phase reactions will be presented using novel experimental methods and theoretical calculations.
4:10 - 4:40 PM
Prof. MyungSoo Kim (Seoul National University, Korea) - Special Lecture
MALDI-tandem mass spectrometry of peptides: kinetics of dissociation and its driving force
4:40 - 5:00 PM
Prof. Pan Yuanjiang (Zhejiang University, China)
Gas-phase chemistry of benzyl cations in unimolecular fragmentation reactions
5:00 - 5:20 PM
Prof. TomoyukiYatsuhashi (Osaka City University, Japan)
Generation and fragmentation of multiply charged molecular ion investigated by nonresonant intense femtosecond laser pulses
5:20 - 5:40 PM
Prof. Adam Trevitt (University of Wollongong, Australia)
Synchrotron PIMS study of phenyl and methylpheny oxidation with isomer-specific detail
Plenary Lecture - Prof. R. Graham Cooks, 6:00 - 6:50 PM
Ambient Ionization and Miniature Mass Spectrometers
August 19, 2011 - Two Parallel Sessions
Session 4 - Novel MS for Biomedical and Environmental Applications, 8:30 - 11:20 AM
Room: Convention Hall 2F (201+202)
Chairs: Dr. Tae-Geol Lee (Korea Research Institute of Standards and Science) & Dr. Jentaie Shiea (Taiwan representative)
Mass spectrometry is essential to biomedical and environmental applications. Recently, there has been an increased demand in homeland security, environmental monitoring, food safety, and clinics for a novel mass spectrometer with a high-portability, high-resolution, and high-throughput capability. In this session, recent changes and developments in mass spectrometry for biomedical and environmental applications will be discussed.
8:30 - 9:00 AM
Prof. Marcos Eberlin (President of International Mass Spectrometry Foundation, Brazil) special lecture
Ease: A New Attribute of Mass Spectrometry
9:00 - 9:20 AM
Prof. Tsutomu Masujima (Hiroshima University, Japan)
Pico-trapping Clinical Analysis by nano-ESI Mass Spectrometry
9:20 - 9:40 AM
Dr. JeongHee Moon (Korea Research Institute of Standards and Science, Korea)
Development of SIMS-MALDI Multimode Molecular Imaging TOF Mass Microscope
Coffee Break (9:40 -9: 50 AM)
9:50 - 10:10 AM
Prof. Chung-Hsuan Chen (Academia Sinica, Taiwan)
Development of Novel Mass Spectrometers and their Biomedical Applications
10:10 - 10:30 AM
Dr. Shuichi Shimma (Osaka University, Japan)
Development and Applications of Miniaturized High-resolution Time-of-flight Mass Spectrometer ¡°MULTUM-S II¡±
10:30 - 10:50 AM
Prof. Zhen Zhou (Shanghai University, China)
Real Time Bipolar Time-of-flight Mass Spectrometer for Analyzing Single Aerosol Particles
10:50 - 11:10 AM
Dr. Yi-Sheng Wang (Academia Sinica, Taiwan)
Simultaneous Positive and Negative Molecular Imaging with Synchronized Dual-Polarity Time-of-Flight Mass Spectrometry
Session 5 - Advances in Analytical Techniques for Separation and MS Detection, 8:30 - 11:20 AM
Room: Convention Hall 2F (203+204)
Chairs: Dr. Jongki Hong (Kyung Hee University) & Dr. Jin-ying Li (China representative)
Recently, mass spectrometers combined with separation instruments have been widely applied to chemistry, physics, pharmaceutics, medicine, biology, environment, and many other fields for the quantitative analysis of interesting targets. This session focuses on the special application of separation and mass spectrometric detection such as structural determination of biopolymers and synthetic polymers, trace metal speciation, profiling analysis of endogenous compounds in biological fluids, and monitoring of hazardous substances using various chromatographic tools and ionization methods..
8:30 - 8:50 AM
Prof. Ryuichi Arakawa (Kansai, University, Japan)
Mass Spectrometric Analysis of Ultrasonic Degradation Products of Poly(ethyleneoxide-block-propyleneoxide) Copolymers
8:50 - 9:10 AM
Prof. Mustafa Ali Mohd (University of Malaya, Malaysia)
Analysis of Urinary and cord blood Bisphenol A and alkylphenols by Gas Chromatograph-Mass Spectrometer from Occupational Exposure at Polycarbonate Moulding Work Area and in cord blood
9:10 - 9:30 AM
Prof. Jae-Min Lim (Changwon National University, Korea)
Glycomic Analyses of Different Genetic Mouse Knock-out Models Associated with Glycosyltransferase
9:30 - 9:50 AM
Dr. Junghyun Son (Smart SCO, Korea)
Identification of Molecular Targets in Forward Chemical Genetics
Coffee Break (9:50 - 10:00 AM)
10:00 - 10:20 AM
Dr. Moutian Wu (China Anti-Doping Agency, China)
Detection of Clenbuterol in Sport with Mass Spectrometry
10:20 - 10:40 AM
Dr. TooruKamata (Forensic Science Laboratory, Osaka Prefectural Police H.Q., Japan)
Mass spectrometry of cannabimimeticaminoalkylindoles (AAIs) ¡°JWH compounds¡±: Characteristics of their EI mass spectra and its application to structure determination of newly encountered AAIs
10:40 - 11:00 AM
Prof. Yeou-Lih Huang (Kaohsiung Medical University, Taiwan)
Microfluidic Device Coupled with ICP Mass Spectrometry for Trace Metal Speciation
11:00 - 11:20 AM
Hideya Kawasaki (Kansai University, Japan)
Human Serum Albumin-Modified Iron Oxide Nanoparticles for Affinity SALDI-MS via the Protein-Drug Interactions
Session 6 - Probing Protein Structures using Mass Spectrometry, 1:30 - 3:10 PM
Room: Convention Hall 2F (201+202)
Chairs: Dr. Hugh I. Kim (POSTECH) & Dr. Manfred Raida (Singapore representative)
The developments of tandem techniques and practical applications of mass spectrometry for examining protein structures become an active field of research. Tandem mass spectrometry (MSn) is now used to understand tertiary and quaternary structures of proteins as well as protein sequences. Tandem ion mobility mass spectrometry (IM-MS) is a powerful tool for screening protein/peptide structures in gas phase. The application of IM-MS has been expanded to probe non-covalent bonded protein complex structures. In this session, recent development of tandem mass spectrometric techniques and their applications to study macromolecular protein structures will be discussed.
1:30 - 1:50 PM
Prof. Satoko Akashi (Yokohama City University)
Mass Spectrometry of Histone Multimers
1:50 - 2:10 PM
Prof. Tara Pukala (University of Adelaide, Australia)
Structural and Mechanistic Insights into Biological Protein Assemblies by Ion Mobility Mass Spectrometry
2:10 - 2:30 PM
Dr. Ji-Eun Lee (Korea Institute of Science and Technology, Korea)
Top-down proteomic analysis by use of molecular weight-based separation and online nanoLC-FTMS
Session 7 - Application of Mass Spectrometry to Nuclear Materials Analysis, 1:30 - 3:10 PM
Room: Convention Hall 2F (203+204)
Chairs: Dr. Kyuseok Song (Korea Atomic Energy Research Institute) & Dr. Suresh K. Aggawal (India representative)
As the nuclear industry becomes one of the spotlighted fields due to the energy crisis, a demand in analytical techniques for nuclear material has been increased.Because of its high accuracy and precision, the role of mass spectrometry in the analysis of nuclear material has become greatly important. In this session, various applications of mass spectrometry to the isotopic analysis of environmental samples for nuclear safeguards, the measurement of nuclear materials, and their related instrumentations will be discussed.
1:30 - 1:50 PM
Prof. Jin-ying Li (China Institute of Atomic Energy, China)
Determination of 240Pu/239Pu at ultra trace level With MC-ICP-MS
1:50 - 2:10 PM
V. Nataraju (Bhabha Atomic Research Centre, India)
Mass Spectrometry Instrumentation - an Indian Perspective
2:10 - 2:30 PM
Dr. Fumitaka Esaka (Japan Atomic Energy Agency, Japan)
Analysis of Individual Uranium and Plutonium Particles with SIMS and ICP-MS for Nuclear Safeguards
2:30 - 2:50 PM
Dr. Yeong-Keong Ha (Korea Atomic Energy Agency, Korea)
Radial Distribution of Isotopic Ratios in Spent Nuclear Fuels by LA-ICP-MS and the Estimated Local Burnup Profiles
2:50 - 3:10 PM
Dr. Jong-Ho Park (Korea Atomic Energy Agency, Korea)
Single Particle Analysis of Uranium Standard Reference Materials using FT-TIMS for Nuclear Safeguards
Session 8 - New Developments in Ionization Method, 2:40 - 5:00 PM
Room: Convention Hall 2F (201+202)
Chairs: Dr. Hun Young So (Korea Research Institute of Standards and Science) & Dr. Stephen Blanksby (Australia representative)
Advances in understanding the detailed mechanisms of atmospheric pressure ionizations (API), such as electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI), have enabled to develop diverse versions of modified API methods. For examples, desorption electrospray ionization (DESI) and direct analysis in real time (DART) ionization have been developed recently. In this session, new developments in API methods and their applications along with their advantages to different aspect of ionization methods will be presented and discussed.
2:40 - 3:00 PM
Prof. Huanwen Chen (East China Institute of Technology, China)
Fundamental Mechanism of Extractive Electrospray Ionization
3:00 - 3:20 PM
Dr. Sung-Chan Jo (Samsung Electronics, Ltd, Korea)
Mass Spectral Analysis of the Additives in Liquid Crystal Displays with Desorption Electrospray Ionization Source
3:20 - 3:40 PM
Prof. Kenzo Hiraoka (University of Yamanashi, Japan)
Single Shot Probe Electrospray: Separation of Analytes with Different Surface Activities
3:40 - 4:00 PM
Prof. Zhongping Yao (The Hong Kong Polytechnic University, Hong Kong)
Tip Spray Mass Spectrometry
4:00 - 4:20 PM
Prof. Yu-Chie Chen (National Chiao Tung University, Taiwan)
Contactless Atmospheric Pressure Ionization Mass Spectrometry
4:20 - 4:40 PM
Dr. George Khairallah (University of Melbourne, Australia)
Are Two Metals Better than One? Synthesis and Reactivity of Ag/Cu Hetero-Metal Clusters
4:40 - 5:00 PM
Professor Xianglei Kong (Nankai University, China)
Large Carbon Cluster Anions Generated by Laser Ablation of Graphene
Session 9 - Fundamentals of Mass Spectrometry II - Odd-electron tandem mass spectrometry, 3:20 - 5:00 PM
Room: Convention Hall 2F (203+204)
Chairs: Dr. Han Bin Oh (Sogang University) & Dr. T-W. Dominic Chan (Hong Kong representative)
In this session, recent results from in-source decay (ISD) in MALDI and odd-electron driven MS/MS methods will be presented. In recent years, active research results have been published related to unique fragmentations in ISD MALDI MS, which exhibit high similarity to those from odd-electron radical fragmentation methods such as ECD (electron capture dissociation) and ETD (electron transfer dissociation) MS. In particular, a focus in this session is given to the characterization of post-translational modifications in peptides/proteins such as disulfide-bonds and phosphorylations.
3:20 - 3:40 PM
Prof. Shuying Liu (Chinese Academy of Sciences, China)
Determination of disulfide bonds in proteins/peptides by MALDI MS
3:40 - 4:00 PM
Prof. Mitsuo Takayama (Yokohama City University, Japan)
Radical-induced fragmentation of phosphorylated-peptides in MALDI
4:00 - 4:20 PM
Prof. Chien-Chen Lai (National Chung Hsing University, Taiwan)
Analysis of Peptides and Phosphopeptides Using Mass Spectrometry with Electron Transfer Dissociation
4:20 - 4:40 PM
Prof. Han Bin Oh (Sogang University, Korea)
TEMPO-based free radical initiated peptide sequencing mass spectrometry (FRIPS MS)
4: 40 - 5:00 PM
Prof. T.-W. Dominic Chan (The Chinese University of Hong Kong, Hong Kong)
ECD of Peptides Adducted with Transition Metal Ions, from Divalent to Trivalent Species
Plenary Lecture - Prof. Yoshinao Wada, 5:20 - 6:10 PM
Classical label-free quantitation for glycomics and glycoproteomics
Room: Convention Hall 2F (201+202+203+204)
Closing Ceremony, 6:00 -6:20 PM
2、 與會心得
這是我第一次出國去參加研討會，緊湊的會議排程只能挑選幾個場次寄去聆聽，看到許多大牌的教授演說著近幾年來的研究成果以及實驗室的研究方向，許多的實驗室研究成果的海報發表，看到將質譜分析技術運用在各式各樣的研究領域，像是蛋白質、脂肪酸、中藥藥草、人類血清、煉油廠廢油、酒精等檢體的測定，乳癌biomarker的發現、前列腺癌患者尿液中phospholipids 當作biomarker，甚至是石油氧化過程未知的反應產物的發掘等等…國外許多研究人員的觀點都與我們國內有差異性，看著這些不同之處也能提供我們靈感，能找出更好的研究方法與方向。在海報發表的部份，更是靈瑯滿目，看完之後才會發現，不管哪種類型題材，不論研究的是深或是淺都有人做，只要看到不同的東西都能給予我們很多想法，能使我們對於未來的實驗有更多的方向。
3、 建 議
感謝學校有這麼好的機制可以補助研究生出國參加研討會，可以擴大學生的視野，做研究上的交流。
4、 攜回資料名稱及內容
(1)大會講義:包含會議議程及各演講者演講內容摘要以及所有發表的
海報摘要。
(2)大會報名費 收據。
(3)參加會議證明。
研習地點:斯洛伐克 Slovakia
研習名稱:2011年亞太質譜年會
研習類別:國際會議(發表論文-Poster)
1、 參加會議經過
因為這次的機會所以有機會第一次到韓國，所以就安排了幾天先到韓國首都首爾市觀光，記憶中張貼海報時間是8月17日早上9點前，所以8/17日當天清晨4.5點起床從首爾車站搭乘6點第一班快速鐵路到達釜山市，約9點半左右到達會場BEXCO釜山展覽中心，報到櫃台竟然空無一人，四處找尋終於找到穿著制服的工作人員，原來是我們搞錯開幕時間了。等到了下午終於開始報到了，緊湊的會議也開始進行，8/18日晚上主辦單位還熱情的準備了晚宴讓與會的會員可以相互認識聯絡感情，8/19日抱著興奮的心情就去會場完成了我的海報張貼。以下就是這次緊湊的會議議程時間表：
August 18, 2011
Session 1 - Mass Spectrometry Driven Proteomics,8:50 - 11:40 AM
Room: Convention Hall 2F (203+204)
Chairs: Dr. Yuju Chen (Academia Sinica) & Dr. Yoshinao Wada (Japan representative)
Mass spectrometry revolutionizes biological sciences. Especially, mass spectrometry plays integral roles in researches of proteomics, where whole proteomes of biological systems are analyzed in the context of their responses either to internal changes or external stimuli, the global networks of molecular interactions, and the accurate identification of complex responses to disease states. In this session, current issues and recent developments of mass spectrometry driven proteomics will be discussed.
8:50 - 9:10 AM
Prof. Yasushi Ishihama (Kyoto University, Japan)
One-Shot Phosphoproteome Analysis by UnidimensionalNanoLC-MS/MS with Highly Efficient Phosphopeptide Enrichment
9:10 - 9:30 AM
Prof. KwangPyo Kim (KonKuk University, Korea)
Systematic Discovery of Nitrated Tyrosine motifs in Nitroproteomics using Affinity Enrichment and LC/MS/MS
9:30 - 9:50 AM
Dr. Pengyuan Yang (Fudan University, China)
Mass Spectrometry Profiling of N-glycopeptides from Serum
9:50 - 10:10 AM
Prof. Hyun JooAhn (Chung Nam National University, Korea)
Human Cell Membrane Glycan Mapping using Mass Spectrometry
Coffee Break (10:10 - 10: 20 AM)
10:20 - 10:40 AM
Prof. Daehee Hwang (Pohang University of Science and Technology, Korea)
Decoding Proteomic Signature Predictive of Chemoresistance in Breast Cancers
10:40 - 11:00 AM
Prof. Siu Kwan Sze (Nanyang Technological University, Singapore)
Roles of Mitochondrial Protein Kinases in Targeted Cancer Therapy
11:00 - 11:20 AM
Prof. Shu-Hui Chen (National Cheng Kung University, Taiwan)
Quantitative Proteomics and Affinity Purifications for Estrogen-Triggered Signal Transduction
11:20 - 11:40 AM
Prof. Manfred Raida (A*STAR, Singapore)
Targeted Mass Spectrometry for Biomarker Detection, Pitfalls and Solutions
Session 2 - Recent Advances in Metabolomics,2:00 - 4:00 PM
Chairs: Dr. Bong Chul Chung (Korea Institute of Science and Technology)&Dr. Mustafa Ali Mohd (Malaysia Representative)
In contrast to classical bio-analyses that mainly focus on single metabolites and/or defined sets of linked reactions and cycles, metabolomics involves the collection of quantitative signatures on a broad series of metabolites to understand metabolic dynamics associated with biological conditions of interest. In this session, recent advances in both method development and biomedical applications for mass spectrometry based metabolomics will be discussed.
2:00 - 2:20 PM
Prof. Zhou Lei (National University of Singapore, Singapore)
Human Tear Proteomics, Metabolomics and Biomarker Discovery in Eye Diseases
2:20 - 2:40 PM
Dr. ZongweiCai (Hong Kong Baptist University, Hong Kong SAR, China)
Mass spectrometry-based metabolomics investigation of aristolochic acids associated with kidney disease
2:40 - 3:00 PM
Prof. GuowangXu (Dalian Institute of Chemical Physics, The Chinese Academy of Science, China)
A functional metabolomics platform based on non-target and target chromatography-mass spectrometry
3:00 - 3:20 PM
Dr. Man-Ho Choi (Korea Institute of Science and Technology, Korea)
Hair Metabolomics in clinical applications of the skin-appendage diseases
3:20 - 3:40 PM
Dr. Anne Bendt (National Unversity of Singapore, Singapore)
Lipidomics: New tools and applications
3:40 - 4:00 PM
Dr. Young-Ran Yoon (KyungpookNational University, Korea)
Metabolomics for Pharmacokinetics, Drug Efficacy, and Drug Toxicity
Session 3 - Fundamentals of Mass Spectrometry I,4:10 - 5:50 PM
Chairs: Dr. Hyun Sik Kim (Korea Basic Science Institute)&Dr. Ryuichi Arakawa (President of MSSJ, Japan representative)
As mass spectrometry is used in biotechnology and nanotechnology more frequently than ever, soft ionization and tandem mass spectrometry are blooming as main players in the field of mass spectrometry. Fragmentation of molecular ions is an essential process of structural elucidation of unknown compound. However, it reduces sensitivity to detect the limited amount of molecular ions generated by ionization techniques. Thereby, better understanding of the fundamental parameters to control the fragmentation process is important. Recent progress of basic understanding in ionization, fragmentation and gas phase reactions will be presented using novel experimental methods and theoretical calculations.
4:10 - 4:40 PM
Prof. MyungSoo Kim (Seoul National University, Korea) - Special Lecture
MALDI-tandem mass spectrometry of peptides: kinetics of dissociation and its driving force
4:40 - 5:00 PM
Prof. Pan Yuanjiang (Zhejiang University, China)
Gas-phase chemistry of benzyl cations in unimolecular fragmentation reactions
5:00 - 5:20 PM
Prof. TomoyukiYatsuhashi (Osaka City University, Japan)
Generation and fragmentation of multiply charged molecular ion investigated by nonresonant intense femtosecond laser pulses
5:20 - 5:40 PM
Prof. Adam Trevitt (University of Wollongong, Australia)
Synchrotron PIMS study of phenyl and methylpheny oxidation with isomer-specific detail
Plenary Lecture - Prof. R. Graham Cooks, 6:00 - 6:50 PM
Ambient Ionization and Miniature Mass Spectrometers
August 19, 2011 - Two Parallel Sessions
Session 4 - Novel MS for Biomedical and Environmental Applications, 8:30 - 11:20 AM
Room: Convention Hall 2F (201+202)
Chairs: Dr. Tae-Geol Lee (Korea Research Institute of Standards and Science) & Dr. Jentaie Shiea (Taiwan representative)
Mass spectrometry is essential to biomedical and environmental applications. Recently, there has been an increased demand in homeland security, environmental monitoring, food safety, and clinics for a novel mass spectrometer with a high-portability, high-resolution, and high-throughput capability. In this session, recent changes and developments in mass spectrometry for biomedical and environmental applications will be discussed.
8:30 - 9:00 AM
Prof. Marcos Eberlin (President of International Mass Spectrometry Foundation, Brazil) special lecture
Ease: A New Attribute of Mass Spectrometry
9:00 - 9:20 AM
Prof. Tsutomu Masujima (Hiroshima University, Japan)
Pico-trapping Clinical Analysis by nano-ESI Mass Spectrometry
9:20 - 9:40 AM
Dr. JeongHee Moon (Korea Research Institute of Standards and Science, Korea)
Development of SIMS-MALDI Multimode Molecular Imaging TOF Mass Microscope
Coffee Break (9:40 -9: 50 AM)
9:50 - 10:10 AM
Prof. Chung-Hsuan Chen (Academia Sinica, Taiwan)
Development of Novel Mass Spectrometers and their Biomedical Applications
10:10 - 10:30 AM
Dr. Shuichi Shimma (Osaka University, Japan)
Development and Applications of Miniaturized High-resolution Time-of-flight Mass Spectrometer ¡°MULTUM-S II¡±
10:30 - 10:50 AM
Prof. Zhen Zhou (Shanghai University, China)
Real Time Bipolar Time-of-flight Mass Spectrometer for Analyzing Single Aerosol Particles
10:50 - 11:10 AM
Dr. Yi-Sheng Wang (Academia Sinica, Taiwan)
Simultaneous Positive and Negative Molecular Imaging with Synchronized Dual-Polarity Time-of-Flight Mass Spectrometry
Session 5 - Advances in Analytical Techniques for Separation and MS Detection, 8:30 - 11:20 AM
Room: Convention Hall 2F (203+204)
Chairs: Dr. Jongki Hong (Kyung Hee University) & Dr. Jin-ying Li (China representative)
Recently, mass spectrometers combined with separation instruments have been widely applied to chemistry, physics, pharmaceutics, medicine, biology, environment, and many other fields for the quantitative analysis of interesting targets. This session focuses on the special application of separation and mass spectrometric detection such as structural determination of biopolymers and synthetic polymers, trace metal speciation, profiling analysis of endogenous compounds in biological fluids, and monitoring of hazardous substances using various chromatographic tools and ionization methods..
8:30 - 8:50 AM
Prof. Ryuichi Arakawa (Kansai, University, Japan)
Mass Spectrometric Analysis of Ultrasonic Degradation Products of Poly(ethyleneoxide-block-propyleneoxide) Copolymers
8:50 - 9:10 AM
Prof. Mustafa Ali Mohd (University of Malaya, Malaysia)
Analysis of Urinary and cord blood Bisphenol A and alkylphenols by Gas Chromatograph-Mass Spectrometer from Occupational Exposure at Polycarbonate Moulding Work Area and in cord blood
9:10 - 9:30 AM
Prof. Jae-Min Lim (Changwon National University, Korea)
Glycomic Analyses of Different Genetic Mouse Knock-out Models Associated with Glycosyltransferase
9:30 - 9:50 AM
Dr. Junghyun Son (Smart SCO, Korea)
Identification of Molecular Targets in Forward Chemical Genetics
Coffee Break (9:50 - 10:00 AM)
10:00 - 10:20 AM
Dr. Moutian Wu (China Anti-Doping Agency, China)
Detection of Clenbuterol in Sport with Mass Spectrometry
10:20 - 10:40 AM
Dr. TooruKamata (Forensic Science Laboratory, Osaka Prefectural Police H.Q., Japan)
Mass spectrometry of cannabimimeticaminoalkylindoles (AAIs) ¡°JWH compounds¡±: Characteristics of their EI mass spectra and its application to structure determination of newly encountered AAIs
10:40 - 11:00 AM
Prof. Yeou-Lih Huang (Kaohsiung Medical University, Taiwan)
Microfluidic Device Coupled with ICP Mass Spectrometry for Trace Metal Speciation
11:00 - 11:20 AM
Hideya Kawasaki (Kansai University, Japan)
Human Serum Albumin-Modified Iron Oxide Nanoparticles for Affinity SALDI-MS via the Protein-Drug Interactions
Session 6 - Probing Protein Structures using Mass Spectrometry, 1:30 - 3:10 PM
Room: Convention Hall 2F (201+202)
Chairs: Dr. Hugh I. Kim (POSTECH) & Dr. Manfred Raida (Singapore representative)
The developments of tandem techniques and practical applications of mass spectrometry for examining protein structures become an active field of research. Tandem mass spectrometry (MSn) is now used to understand tertiary and quaternary structures of proteins as well as protein sequences. Tandem ion mobility mass spectrometry (IM-MS) is a powerful tool for screening protein/peptide structures in gas phase. The application of IM-MS has been expanded to probe non-covalent bonded protein complex structures. In this session, recent development of tandem mass spectrometric techniques and their applications to study macromolecular protein structures will be discussed.
1:30 - 1:50 PM
Prof. Satoko Akashi (Yokohama City University)
Mass Spectrometry of Histone Multimers
1:50 - 2:10 PM
Prof. Tara Pukala (University of Adelaide, Australia)
Structural and Mechanistic Insights into Biological Protein Assemblies by Ion Mobility Mass Spectrometry
2:10 - 2:30 PM
Dr. Ji-Eun Lee (Korea Institute of Science and Technology, Korea)
Top-down proteomic analysis by use of molecular weight-based separation and online nanoLC-FTMS
Session 7 - Application of Mass Spectrometry to Nuclear Materials Analysis, 1:30 - 3:10 PM
Room: Convention Hall 2F (203+204)
Chairs: Dr. Kyuseok Song (Korea Atomic Energy Research Institute) & Dr. Suresh K. Aggawal (India representative)
As the nuclear industry becomes one of the spotlighted fields due to the energy crisis, a demand in analytical techniques for nuclear material has been increased.Because of its high accuracy and precision, the role of mass spectrometry in the analysis of nuclear material has become greatly important. In this session, various applications of mass spectrometry to the isotopic analysis of environmental samples for nuclear safeguards, the measurement of nuclear materials, and their related instrumentations will be discussed.
1:30 - 1:50 PM
Prof. Jin-ying Li (China Institute of Atomic Energy, China)
Determination of 240Pu/239Pu at ultra trace level With MC-ICP-MS
1:50 - 2:10 PM
V. Nataraju (Bhabha Atomic Research Centre, India)
Mass Spectrometry Instrumentation - an Indian Perspective
2:10 - 2:30 PM
Dr. Fumitaka Esaka (Japan Atomic Energy Agency, Japan)
Analysis of Individual Uranium and Plutonium Particles with SIMS and ICP-MS for Nuclear Safeguards
2:30 - 2:50 PM
Dr. Yeong-Keong Ha (Korea Atomic Energy Agency, Korea)
Radial Distribution of Isotopic Ratios in Spent Nuclear Fuels by LA-ICP-MS and the Estimated Local Burnup Profiles
2:50 - 3:10 PM
Dr. Jong-Ho Park (Korea Atomic Energy Agency, Korea)
Single Particle Analysis of Uranium Standard Reference Materials using FT-TIMS for Nuclear Safeguards
Session 8 - New Developments in Ionization Method, 2:40 - 5:00 PM
Room: Convention Hall 2F (201+202)
Chairs: Dr. Hun Young So (Korea Research Institute of Standards and Science) & Dr. Stephen Blanksby (Australia representative)
Advances in understanding the detailed mechanisms of atmospheric pressure ionizations (API), such as electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI), have enabled to develop diverse versions of modified API methods. For examples, desorption electrospray ionization (DESI) and direct analysis in real time (DART) ionization have been developed recently. In this session, new developments in API methods and their applications along with their advantages to different aspect of ionization methods will be presented and discussed.
2:40 - 3:00 PM
Prof. Huanwen Chen (East China Institute of Technology, China)
Fundamental Mechanism of Extractive Electrospray Ionization
3:00 - 3:20 PM
Dr. Sung-Chan Jo (Samsung Electronics, Ltd, Korea)
Mass Spectral Analysis of the Additives in Liquid Crystal Displays with Desorption Electrospray Ionization Source
3:20 - 3:40 PM
Prof. Kenzo Hiraoka (University of Yamanashi, Japan)
Single Shot Probe Electrospray: Separation of Analytes with Different Surface Activities
3:40 - 4:00 PM
Prof. Zhongping Yao (The Hong Kong Polytechnic University, Hong Kong)
Tip Spray Mass Spectrometry
4:00 - 4:20 PM
Prof. Yu-Chie Chen (National Chiao Tung University, Taiwan)
Contactless Atmospheric Pressure Ionization Mass Spectrometry
4:20 - 4:40 PM
Dr. George Khairallah (University of Melbourne, Australia)
Are Two Metals Better than One? Synthesis and Reactivity of Ag/Cu Hetero-Metal Clusters
4:40 - 5:00 PM
Professor Xianglei Kong (Nankai University, China)
Large Carbon Cluster Anions Generated by Laser Ablation of Graphene
Session 9 - Fundamentals of Mass Spectrometry II - Odd-electron tandem mass spectrometry, 3:20 - 5:00 PM
Room: Convention Hall 2F (203+204)
Chairs: Dr. Han Bin Oh (Sogang University) & Dr. T-W. Dominic Chan (Hong Kong representative)
In this session, recent results from in-source decay (ISD) in MALDI and odd-electron driven MS/MS methods will be presented. In recent years, active research results have been published related to unique fragmentations in ISD MALDI MS, which exhibit high similarity to those from odd-electron radical fragmentation methods such as ECD (electron capture dissociation) and ETD (electron transfer dissociation) MS. In particular, a focus in this session is given to the characterization of post-translational modifications in peptides/proteins such as disulfide-bonds and phosphorylations.
3:20 - 3:40 PM
Prof. Shuying Liu (Chinese Academy of Sciences, China)
Determination of disulfide bonds in proteins/peptides by MALDI MS
3:40 - 4:00 PM
Prof. Mitsuo Takayama (Yokohama City University, Japan)
Radical-induced fragmentation of phosphorylated-peptides in MALDI
4:00 - 4:20 PM
Prof. Chien-Chen Lai (National Chung Hsing University, Taiwan)
Analysis of Peptides and Phosphopeptides Using Mass Spectrometry with Electron Transfer Dissociation
4:20 - 4:40 PM
Prof. Han Bin Oh (Sogang University, Korea)
TEMPO-based free radical initiated peptide sequencing mass spectrometry (FRIPS MS)
4: 40 - 5:00 PM
Prof. T.-W. Dominic Chan (The Chinese University of Hong Kong, Hong Kong)
ECD of Peptides Adducted with Transition Metal Ions, from Divalent to Trivalent Species
Plenary Lecture - Prof. Yoshinao Wada, 5:20 - 6:10 PM
Classical label-free quantitation for glycomics and glycoproteomics
Room: Convention Hall 2F (201+202+203+204)
Closing Ceremony, 6:00 -6:20 PM
2、 與會心得
這是我第一次出國去參加研討會，緊湊的會議排程只能挑選幾個場次寄去聆聽，看到許多大牌的教授演說著近幾年來的研究成果以及實驗室的研究方向，許多的實驗室研究成果的海報發表，看到將質譜分析技術運用在各式各樣的研究領域，像是蛋白質、脂肪酸、中藥藥草、人類血清、煉油廠廢油、酒精等檢體的測定，乳癌biomarker的發現、前列腺癌患者尿液中phospholipids 當作biomarker，甚至是石油氧化過程未知的反應產物的發掘等等…國外許多研究人員的觀點都與我們國內有差異性，看著這些不同之處也能提供我們靈感，能找出更好的研究方法與方向。在海報發表的部份，更是靈瑯滿目，看完之後才會發現，不管哪種類型題材，不論研究的是深或是淺都有人做，只要看到不同的東西都能給予我們很多想法，能使我們對於未來的實驗有更多的方向。
3、 建 議
感謝學校有這麼好的機制可以補助研究生出國參加研討會，可以擴大學生的視野，做研究上的交流。
4、 攜回資料名稱及內容
(1)大會講義:包含會議議程及各演講者演講內容摘要以及所有發表的
海報摘要。
(2)大會報名費 收據。
(3)參加會議證明。
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